Talk by Angelika Mustroph, University Bayreuth – University of Copenhagen

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Talk by Angelika Mustroph, University Bayreuth

On 10 September at 15.00-16.00 Prof. Dr. Angelika Mustroph from Bayreuth Center of Ecology and Environmental Research, University Bayreuth will give a talk on:

Characteristics of plant phosphofructokinases

Unlike animals, plants possess two types of phosphofructokinases. One form performs the glycolytic reaction from fructose-6-phosphate to fructose-1,6-bisphosphate by use of ATP as the energy source, similar as in animals and fungi. Therefore it is referred to as the ATP-dependent phosphofructokinase or PFK. The other form uses pyrophosphate (PPi) as the energy source, and is referred to as PPi-dependent phosphofructokinase or more exactly, pyrophosphate fructose-6-phosphate phosphotransferase (PFP).

Multiple isoforms of PFKs exist in plants, in the cytosol and the chloroplast. This irreversible enzyme is believed to have the major glycolytic function, but some isoforms show specific characteristics which are not yet fully understood. For example, Arabidopsis thaliana contains seven genes for PFKs. The proteins differ in enzyme activity, intracellular localization and redox regulation and might fulfil also functions besides glycolysis.

The enzyme PFP is restricted to plants and a few microorganisms. The function of this reversible enzyme is not yet fully understood. It is hypothesized that PFP plays a role under stress conditions, for example in rice under oxygen deficiency stress. There, it could replace PFK and in such a way save ATP. However, Arabidopsis or potato plants with low PFP activity do not show any phenotype under normal or oxygen-deficient conditions. Possibly, the importance of PFP can vary between plant species and conditions.

Angelika Mustroph has been invited to give a talk by Tom Hamborg Nielsen, Section for Molecular Plant Biology, Department of Plant and Environmental Sciences, University of Copenhagen.