Job vacancies – University of Copenhagen

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Copenhagen Plant Science Centre > Job vacancies


 

Job vacancies

3 open positions for the HOPE project

Copenhagen Plant Science Centre are looking for a postdoc, a PhD and a laoratory technician for the project “Harnessing the power of Oxidative Enzymes” (HOPE) funded by the Novo Nordisk Foundation:

Post Doctoral fellow in oxidative enzymology

 
Department of Plant and Environmental Sciences, Faculty of Science at University of Copenhagen is offering a post doctoral position in oxidative enzymology, commencing January 1st, 2018 or as soon as possible thereafter. 

Project description 
The strategic research initiative HOPE addresses the pressing challenge of studying some of the most powerful oxidative enzymes discovered in Nature, known as lytic polysaccharide monooxygenases or LPMOs. LPMOs are essential for initiating the enzymatic decomposition of abundant recalcitrant biopolymers such as chitin and cellulose. In HOPE, we strive to use insight into enzyme mechanism to understand the role of LPMOs in their biological context. A dedicated laboratory for oxidative enzymology is currently being established. Biochemical characterization of LPMOs is complicated by the involvement of two substrates and a reducing agent in catalysis. This laboratory is charged with the task of being the protein chemistry hub of HOPE. The laboratory has a full-time technical assistant employed. 

Read the full job posting here.

PhD fellow in identification and characterization of inhibitors of lytic polysaccharide monooxygenases (LPMOs)

 
Department of Plant and Environmental Sciences, Faculty of Science at University of Copenhagen is offering a PhD scholarship in identification and characterization of plant derived inhibitors of lytic polysaccharide monooxygenases (LPMOs), commencing February 1st, 2018 or as soon as possible thereafter. 

Project description
The main aim of the project is to contribute to the structural and functional understanding of LPMOs as part of a new project between several Departments at the University of Copenhagen and DTU. Plants are likely to produce compounds that inhibit the catalytic activity of LPMOs. Enzyme inhibitors are broadly divided into noncovalent and covalent inhibitors, with members of each class having different applications. LPMO inhibitors have great potential as both a drug candidate and as control agent for agricultural applications. The inhibitors might be specific for LPMOs and can potentially be induced during bacterial or fungal infections. In this project we aim at isolating one or more of these inhibitors, identifying them using mass spectrometry and characterizing them further for instance by LPMO co-crystallization experiments.  

We are seeking a motivated and creative PhD student displaying enthusiasm and good interpersonal and communication skills. Candidates with demonstrated skills in molecular biology, biochemistry, HPLC, GC-MS, LC-MS, enzyme activity assays, and assay developments are preferred. Prior documented knowledge within enzymology and plant specialized metabolism will be an advantage. 

Read the full job posting here.

Laborant til SCIENCE Institut for plante- og miljøvidenskab
  

Copenhagen Plant Science Center ved Institut for Plante- og Miljøvidenskab, Det Natur- og Biovidenskabelige Fakultet (SCIENCE), Københavns Universitet søger en laborant med tiltrædelse hurtigst muligt.
 
I dette job får du en nøglerolle i etableringen af et nyt laboratorium. Laboratoriet, som designes til arbejde med oxidative enzymer, vil blive opbygget i helt nye lokaler på Frederiksberg. Her vil du være del af en dynamisk gruppe af forskere og studerende.