Job vacancies – University of Copenhagen

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Copenhagen Plant Science Centre > Job vacancies


 

Job vacancies

PhD fellow in non-coding Transcription

Copenhagen Plant Science Centre (CPSC) at the Department of Plant and Environmental Sciences, Faculty of Science at University of Copenhagen is seeking a candidate for a 3-year PhD-scholarship commencing 1 September 2017 or as soon as possible thereafter.

Project description
The Marquardt lab is interested in understanding the functional significance of abundant yet mysterious non-coding sequences present in genomes. We employ cutting edge budding yeast technology to identify the molecular mechanisms controlling transcription of non-coding sequences into long non-coding RNA (lncRNA). We disrupt these regulatory mechanisms in higher organisms such as Arabidopsis to study the functional roles of non-coding transcription in environmental responses.   

We are looking for a PhD student enthusiastic about lncRNA transcription. Your main project will be to identify novel pathways controlling divergent non-coding transcription from gene promoters. You will develop and apply high-throughput genomics approaches to identify novel players. Further molecular characterization of these pathways will enable you to study the function of divergent long non-coding transcription in yeast, plant and human. The project is inter-disciplinary; you will work at the interface of the research areas: Chromatin Biology, Pol II Transcription and Non-Coding RNA. Your enthusiasm will help you to develop a current molecular understanding of these fields to push the boundaries of current knowledge. 

Application deadline: 15 June 2017

Read the full job posting.

  

Postdoc within non-coding transcription

Copenhagen Plant Science Centre (CPSC) at the Department of Plant and Environmental Sciences wishes to appoint a highly motivated postdoc in the field of non-coding transcription commencing on 1st September 2017 or as soon as possible thereafter. The period of employment is 2 years with the possibility for extension.

Project description
The Marquardt lab is interested in understanding the functional significance of abundant yet mysterious non-coding sequences present in genomes. We employ cutting edge budding yeast technology to identify the molecular mechanisms controlling transcription of non-coding sequences into non-coding RNA. We disrupt these regulatory mechanisms in complex organisms such as Arabidopsis to study the functional roles of non-coding transcription, particularly in environmental responses.   

We are looking for a postdoc to advance our understanding of the molecular mechanisms and biological roles of long non-coding RNA transcription. We recently elucidated the genetic architecture of divergent non-coding transcription in budding yeast. You have the opportunity to design, perform and analyze Next-Generation Sequencing experiments to identify the genome-wide effect and mechanism of identified regulators. You will draw from an excellent research environment in the areas of RNA biology, chromatin Biology and transcription to design and conduct these experiments. You will test how the molecular mechanisms affecting regulation by long-coding RNA transcription identified budding yeast translate into higher organisms. Our progress with gene repression by the process of long non-coding RNA transcription in Arabidopsis indicates how identified molecular mechanisms may be linked broadly to biological effects. Your results will inform experiments of our lab and collaborators, we are therefore looking for a postdoc that stimulates productive and synergistic interactions with the lab members. You are working on the edge of current knowledge, and will keep up to date with the relevant literature to drive this project into the most interesting direction.  

Application deadline: 15 June 2017

Read the full job posting.